Antifungal Potential of Synthetic Peptides against <i>Cryptococcus neoformans</i>: Mechanism of Action Studies Reveal Synthetic Peptides Induce Membrane-Pore Formation, DNA Degradation, and Apoptosis

• Main Authors: Tawanny K. B. Aguiar (Author), Nilton A. S. Neto (Author), Cleverson D. T. Freitas (Author), Ayrles F. B. Silva (Author), Leandro P. Bezerra (Author), Ellen A. Malveira (Author), Levi A. C. Branco (Author), Felipe P. Mesquita (Author), Gustavo H. Goldman (Author), Luciana M. R. Alencar (Author), Jose T. A. Oliveira (Author), Ralph Santos-Oliveira (Author), Pedro F. N. Souza (Author)
• Format: Book
• Published: MDPI AG, 2022-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<i>Cryptococcus neoformans</i> is a human-pathogenic yeast responsible for pneumonia and meningitis, mainly in patients immunocompromised. Infections caused by <i>C. neoformans</i> are a global health concern. Synthetic antimicrobial peptides (SAMPs) have emerged as alternati...