Periodontitis Gingival Tissue Exosomes Cross and Compromise Human BBB in an In-Vitro 3D Model

OBJECTIVES: The objective of this aim was to test the hypothesis that human gingival EXO from PD patients (PD-EXO) promote BMEC dysfunction and increase BBB permeability by degrading tight junction proteins, using a human in-vitro 3D BBB model. METHODS: EXO purified from human gingiva (n=7) of stage...

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Main Authors: Tigerwin Yang (Author), Ranya Elsayed, PhD MBA (Author)
Format: Book
Published: Elsevier, 2024-09-01T00:00:00Z.
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3rd Floor Main Library

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