Structural determinants for subnanomolar inhibition of the secreted aspartic protease Sapp1p from Candida parapsilosis

Pathogenic Candida albicans yeasts frequently cause infections in hospitals. Antifungal drugs lose effectiveness due to other Candida species and resistance. New medications are thus required. Secreted aspartic protease of C. parapsilosis (Sapp1p) is a promising target. We have thus solved the cryst...

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Main Authors: Jiří Dostál (Author), Jiří Brynda (Author), Lucie Vaňková (Author), Syeda Rehana Zia (Author), Iva Pichová (Author), Olga Heidingsfeld (Author), Martin Lepšík (Author)
Format: Book
Published: Taylor & Francis Group, 2021-01-01T00:00:00Z.
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3rd Floor Main Library

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