Metabolic therapy and bioenergetic analysis: The missing piece of the puzzle

• Main Authors: Tomás Duraj (Author), Josefa Carrión-Navarro (Author), Thomas N. Seyfried (Author), Noemí García-Romero (Author), Angel Ayuso-Sacido (Author)
• Format: Book
• Published: Elsevier, 2021-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Aberrant metabolism is recognized as a hallmark of cancer, a pillar necessary for cellular proliferation. Regarding bioenergetics (ATP generation), most cancers display a preference not only toward aerobic glycolysis ("Warburg effect") and glutaminolysis (mitochondrial substrat...