Predicting and Understanding the Pathology of Single Nucleotide Variants in Human <i>COQ</i> Genes

• Main Authors: Sining Wang (Author), Akash Jain (Author), Noelle Alexa Novales (Author), Audrey N. Nashner (Author), Fiona Tran (Author), Catherine F. Clarke (Author)
• Format: Book
• Published: MDPI AG, 2022-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Coenzyme Q (CoQ) is a vital lipid that functions as an electron carrier in the mitochondrial electron transport chain and as a membrane-soluble antioxidant. Deficiencies in CoQ lead to metabolic diseases with a wide range of clinical manifestations. There are currently few treatments that can slow o...