Gastrodin Alleviates Oxidative Stress-Induced Apoptosis and Cellular Dysfunction in Human Umbilical Vein Endothelial Cells via the Nuclear Factor-Erythroid 2-Related Factor 2/Heme Oxygenase-1 Pathway and Accelerates Wound Healing In Vivo

• Main Authors: Jialiang Lin (Author), Yifeng Shi (Author), Jiansen Miao (Author), Yuhao Wu (Author), Hao Lin (Author), Jianwei Wu (Author), Weimin Zeng (Author), Fangzhou Qi (Author), Chen Liu (Author), Xiangyang Wang (Author), Haiming Jin (Author)
• Format: Book
• Published: Frontiers Media S.A., 2019-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Aims: To explore the effect and mechanism of gastrodin (GAS) on human umbilical vein endothelial cells (HUVECs) apoptosis induced by oxidative stress and its function in wound healing.Main methods: HUVECs were incubated with tert-butyl hydroperoxide (TBHP) to induce endothelial cell dysfunction and...