Spatial resolved transcriptomics reveals distinct cross-talk between cancer cells and tumor-associated macrophages in intrahepatic cholangiocarcinoma

• Main Authors: Zhao-Ru Dong (Author), Meng-Ya Zhang (Author), Ling-Xin Qu (Author), Jie Zou (Author), Yong-Heng Yang (Author), Yun-Long Ma (Author), Chun-Cheng Yang (Author), Xue-Lei Cao (Author), Li-Yuan Wang (Author), Xiao-Lu Zhang (Author), Tao Li (Author)
• Format: Book
• Published: BMC, 2024-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Multiple studies have shown that tumor-associated macrophages (TAMs) promote cancer initiation and progression. However, the reprogramming of macrophages in the tumor microenvironment (TME) and the cross-talk between TAMs and malignant subclones in intrahepatic cholangiocarcinoma...