Cytokine-Induced Killer (CIK) Cells, In Vitro Expanded under Good Manufacturing Process (GMP) Conditions, Remain Stable over Time after Cryopreservation

• Main Authors: Katia Mareschi (Author), Aloe Adamini (Author), Sara Castiglia (Author), Deborah Rustichelli (Author), Laura Castello (Author), Alessandra Mandese (Author), Marco Leone (Author), Giuseppe Pinnetta (Author), Giulia Mesiano (Author), Ivana Ferrero (Author), Franca Fagioli (Author)
• Format: Book
• Published: MDPI AG, 2020-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Cytokine-induced killer (CIK) cells are advanced therapy medicinal products, so their production and freezing process has to be validated before their clinical use, to verify their stability as a drug formulation according to the good manufacturing practice (GMP) guidelines. We designed a stability...