p57 Suppresses the Pluripotency and Proliferation of Mouse Embryonic Stem Cells by Positively Regulating p53 Activation

• Main Authors: Na Li (Author), Zhaoyu Du (Author), Yunxiang Li (Author), Wenjing Xu (Author), Yumei Yang (Author), Haodong Peng (Author), Tianxiang Song (Author), Qihua Qin (Author), Huining Lei (Author), Jinlian Hua (Author)
• Format: Book
• Published: Hindawi Limited, 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Embryonic stem cells (ESCs) are pluripotent stem cells that have indefinite self-renewal capacities under appropriate culture conditions in vitro. The pluripotency maintenance and proliferation of these cells are delicately governed by the concert effect of a complex transcriptional regulatory netwo...