Cover Image

Physiologically-Based Pharmacokinetic Modelling to Predict the Pharmacokinetics and Pharmacodynamics of Linezolid in Adults and Children with Tuberculous Meningitis

Linezolid is used off-label for treatment of central nervous system infections. However, its pharmacokinetics and target attainment in cranial cerebrospinal fluid (CSF) in tuberculous meningitis patients is unknown. This study aimed to predict linezolid cranial CSF concentrations and assess attainme...

Full description

Saved in:

Bibliographic Details
Main Authors:	Carlijn H. C. Litjens (Author), Laurens F. M. Verscheijden (Author), Elin M. Svensson (Author), Petra H. H. van den Broek (Author), Hedwig van Hove (Author), Jan B. Koenderink (Author), Frans G. M. Russel (Author), Rob E. Aarnoutse (Author), Lindsey H. M. te Brake (Author)
Format:	Book
Published:	MDPI AG, 2023-04-01T00:00:00Z.
Subjects:	article
Online Access:	Connect to this object online.
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Completing the Enalaprilat Excretion Pathway-Renal Handling by the Proximal Tubule
by: Nori J. L. Smeets, et al.
Published: (2020)

Pharmacokinetics of Linezolid and Ertapenem in experimental parapneumonic pleural effusion
by: Tsatsakis Aristidis, et al.
Published: (2010)

Comprehensive Therapeutic Approaches to Tuberculous Meningitis: Pharmacokinetics, Combined Dosing, and Advanced Intrathecal Therapies
by: Ahmad Khalid Madadi, et al.
Published: (2024)

Effect of coadministration of rifampicin on the pharmacokinetics of linezolid: clinical and animal studies
by: Satsuki Hashimoto, et al.
Published: (2018)

Population pharmacokinetics and dose evaluations of linezolid in the treatment of multidrug-resistant tuberculosis
by: Haoyue Zhang, et al.
Published: (2023)

Linezolid Pharmacokinetics in Critically Ill Patients: Continuous Versus Intermittent Infusion
by: Ligia-Ancuța Hui, et al.
Published: (2024)

Linezolid Pharmacokinetics and Its Association with Adverse Drug Reactions in Patients with Drug-Resistant Pulmonary Tuberculosis
by: Chandrasekaran Padmapriyadarsini, et al.
Published: (2023)

The Population Pharmacokinetics of Meropenem in Adult Patients With Rifampicin-Sensitive Pulmonary Tuberculosis
by: Ahmed A. Abulfathi, et al.
Published: (2021)

Modeling tuberculous meningitis in zebrafish using Mycobacterium marinum
by: Lisanne M. van Leeuwen, et al.
Published: (2014)

Population Pharmacokinetic/Pharmacodynamic Study of Linezolid in Hospital-Acquired Pneumonia Patients with Renal Insufficiency
by: Xu J, et al.
Published: (2024)

Pharmacokinetic analysis of linezolid for multidrug resistant tuberculosis at a tertiary care centre in Mumbai, India
by: Juan Eduardo Resendiz-Galvan, et al.
Published: (2023)

Pharmacokinetic/Pharmacodynamic Analysis of Tedizolid Phosphate Compared to Linezolid for the Treatment of Infections Caused by Gram-Positive Bacteria
by: Alicia Rodríguez-Gascón, et al.
Published: (2021)

Novel Population Pharmacokinetic Model for Linezolid in Critically Ill Patients and Evaluation of the Adequacy of the Current Dosing Recommendation
by: Amaia Soraluce, et al.
Published: (2020)

Towards Improved Management of Tuberculous Bloodstream Infections: Pharmacokinetic Considerations with Suggestions for Better Treatment Outcomes
by: Charles Okot Odongo, et al.
Published: (2022)

Comparative Pharmacokinetic Study for Linezolid and Two Novel Antibacterial Oxazolidinone Derivatives in Rabbits: Can Differences in the Pharmacokinetic Properties Explain the Discrepancies between Their In Vivo and In Vitro Antibacterial Activities?
by: Mohsen A. Hedaya, et al.
Published: (2017)

Annual risk of tuberculous infection
by: G.M. Cauthen, et al.

Do not forget tuberculous meningitis
by: David Tibbutt
Published: (2015)

Neurologic Sequelae of Tuberculous Meningitis
by: J Gordon Millichap
Published: (2005)

Population pharmacokinetics of olprinone in healthy male volunteers
by: Kunisawa T, et al.
Published: (2014)

Optimizing the design of a pharmacokinetic trial to evaluate the dosing scheme of a novel tuberculosis drug in children living with or without HIV
by: Grace Montepiedra, et al.
Published: (2024)

A population pharmacokinetics analysis assessing the exposure of raltegravir once‐daily 1200 mg in pregnant women living with HIV
by: Vera E. Bukkems, et al.
Published: (2021)

Pharmacokinetics and pharmacodynamics of medication in asphyxiated newborns during controlled hypothermia. The PharmaCool multicenter study
by: de Haan Timo R, et al.
Published: (2012)

Pharmacokinetics and pharmacodynamics of linezolid in plasma/cerebrospinal fluid in patients with cerebral hemorrhage after lateral ventricular drainage by Monte Carlo simulation
by: Wu X, et al.
Published: (2018)

Pharmacokinetics of Linezolid Dose Adjustment for Creatinine Clearance in Critically Ill Patients: A Multicenter, Prospective, Open-Label, Observational Study
by: Wang X, et al.
Published: (2021)

Rituximab pharmacokinetic and pharmacokinetic-pharmacodynamic evaluation based on a study in diffuse large B‐cell lymphoma: Influence of tumor size on pharmacokinetic and assessment of pharmacokinetic similarity
by: Robin J. Svensson, et al.
Published: (2023)

A pharmacokinetic comparison of two voriconazole formulations and the effect of CYP2C19 polymorphism on their pharmacokinetic profiles
by: Chung H, et al.
Published: (2015)

Combined quantitative tuberculosis biomarker model for time-to-positivity and colony forming unit to support tuberculosis drug development
by: Rami Ayoun Alsoud, et al.
Published: (2023)

MODERN DIAGNOSTIC METHODS OF TUBERCULOUS MENINGITIS AMONG CHILDREN'S POPULATION
by: B.P. SHARIPOV, et al.
Published: (2018)

Linezolid-Induced Thrombocytopenia in Patients with Renal Impairment: A Case Series, Review and Dose Advice
by: S. R. E. Laarhuis, et al.
Published: (2024)

Acute ischemic stroke in tuberculous meningitis
by: Yi-Jia Guo, et al.
Published: (2024)

Influence of Probenecid on the Pharmacokinetics and Pharmacodynamics of Sorafenib
by: Koen G. A. M. Hussaarts, et al.
Published: (2020)

Tuberculous Granuloma
by: T M Uma Maheswari, et al.
Published: (2011)

The relation of BCG vaccination and severe malnutrition with the occurrence of tuberculous meningitis
by: Nofareni Nofareni, et al.
Published: (2016)

Machine Learning and Pharmacometrics for Prediction of Pharmacokinetic Data: Differences, Similarities and Challenges Illustrated with Rifampicin
by: Lina Keutzer, et al.
Published: (2022)

The role of Physiotherapy in the management of Tuberculous Meningitis in children
by: C. A. Liggins
Published: (1977)

Importance of differentiating Mycobaterium bovis in tuberculous meningitis
by: Alejandra Gonzàlez-Duarte, et al.
Published: (2011)

Potential of Host Serum Protein Biomarkers in the Diagnosis of Tuberculous Meningitis in Children
by: Charles M. Manyelo, et al.
Published: (2019)

The Use of Linezolid in Children with Malignant Solid Tumors
by: H.I. Klymniuk, et al.
Published: (2015)

The global burden of tuberculous meningitis in adults: A modelling study
by: Peter J. Dodd, et al.
Published: (2021)

The global burden of tuberculous meningitis in adults: A modelling study.
by: Peter J Dodd, et al.
Published: (2021)