The Effects of Pitavastatin on Nuclear Factor-Kappa B and ICAM-1 in Human Saphenous Vein Graft Endothelial Culture

• Main Authors: Bulent Demir (Author), Burak Onal (Author), Sibel Ozyazgan (Author), Esra Demir (Author), Vedat Bakuy (Author), Ahmet Gokhan Akkan (Author)
• Format: Book
• Published: Hindawi-Wiley, 2019-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective. To study pitavastatin's effects on nuclear factor-kappa B (NF-κB ) and adhesion molecules in human saphenous vein graft endothelial culture indicating its pleotropic properties. Materials and Method. Low-dose (0.1 μM/L) and high-dose (1μM/L) pitavastatin calcium were administered as...