Perinatal Management of Bart's Hemoglobinopathy: Paradoxical Effects of Intrauterine, Transplacental, and Partial Exchange Transfusions

• Päätekijät: Mark Curran (Tekijä), Michel Mikhael (Tekijä), Wang-Dar Sun (Tekijä), Jina Lim (Tekijä), Anna Leung (Tekijä), Gira Morchi (Tekijä), Ramen H. Chmait (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: Thieme Medical Publishers, Inc., 2020-01-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

We describe a fetus at 24 3/7 weeks' gestation that showed ultrasound evidence of anemia, hydrops, and severe growth restriction. Both parents were known to be cis heterozygous carriers for SEA α-thalassemia deletion (αα/-). Cordocentesis confirmed fetal anemia and homozygous α-thalassemia (−/−...