Synthesis of 4-aryl-2,6-dimethyl-3,5-bis-N-(aryl)-carbamoyl-1,4-dihydropyridines as novel skin protecting and anti-aging agents

• Main Authors: Aamer Saeed (Author), Danish Shahzad (Author), Fayaz Ali Larik (Author), Pervaiz Ali Channar (Author), Haroon Mahfooz (Author), Qamar Abbas (Author), Mubashir Hassan (Author), Hussain Raza (Author), Sung-Yum Seo (Author), Ghulam Shabir (Author)
• Format: Book
• Published: Bangladesh Pharmacological Society, 2017-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

A series of 4-aryl-2,6-dimethyl-3,5-bis-N-(aryl)-carbamoyl-1,4-dihydropyri-dines 6a-6h were prepared by using the one-pot three component synthetic method. The target compounds 6a-6h were synthesized by reacting two molar equivalents of ketone functionality and one mole of aromatic aldehydes in ammo...