A systematic review and integrative approach to decode the common molecular link between levodopa response and Parkinson's disease

• Main Authors: Debleena Guin (Author), Manish Kumar Mishra (Author), Puneet Talwar (Author), Chitra Rawat (Author), Suman S. Kushwaha (Author), Shrikant Kukreti (Author), Ritushree Kukreti (Author)
• Format: Book
• Published: BMC, 2017-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background PD is a progressive neurodegenerative disorder commonly treated by levodopa. The findings from genetic studies on adverse effects (ADRs) and levodopa efficacy are mostly inconclusive. Here, we aim to identify predictive genetic biomarkers for levodopa response (LR) and determine...