The MEMIC is an ex vivo system to model the complexity of the tumor microenvironment

• Main Authors: Libuše Janská (Author), Libi Anandi (Author), Nell C. Kirchberger (Author), Zoran S. Marinkovic (Author), Logan T. Schachtner (Author), Gizem Guzelsoy (Author), Carlos Carmona-Fontaine (Author)
• Format: Book
• Published: The Company of Biologists, 2021-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

There is an urgent need for accurate, scalable and cost-efficient models of the tumor microenvironment. Here, we detail how to fabricate and use the metabolic microenvironment chamber (MEMIC) - a 3D-printed ex vivo model of intratumoral heterogeneity. A major driver of the cellular and molecular div...