Effect of Polymer Permeability and Solvent Removal Rate on <i>In Situ</i> Forming Implants: Drug Burst Release and Microstructure

• Main Authors: Xiaowei Zhang (Author), Liqun Yang (Author), Chong Zhang (Author), Danhua Liu (Author), Shu Meng (Author), Wei Zhang (Author), Shengnan Meng (Author)
• Format: Book
• Published: MDPI AG, 2019-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

To explore the mechanism of drug release and depot formation of in situ forming implants (ISFIs), osthole-loaded ISFIs were prepared by dissolving polylactide, poly(lactide-<i>co</i>-glycolide), polycaprolactone, or poly(trimethylene carbonate) in different organic solvents, including &l...