Doxazosin stimulates galectin-3 expression and collagen synthesis in HL-1 cardiomyocytes independent of protein kinase C pathway

Doxazosin, a drug commonly prescribed for hypertension and prostate disease, increases heart failure risk. However, the underlying mechanism remains unclear. Galectin-3 is an important mediator that plays a pathogenic role in cardiac hypertrophy and heart failure. In the present study, we investigat...

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Main Authors: Xiaoqian Qian (Author), Mingyang Li (Author), Mary B Wagner (Author), Guangping Chen (Author), Xiang Song (Author)
Format: Book
Published: Frontiers Media S.A., 2016-12-01T00:00:00Z.
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