Celastrol induces ferroptosis in activated HSCs to ameliorate hepatic fibrosis via targeting peroxiredoxins and HO-1
Ferroptosis is a form of regulated cell death, characterized by excessive membrane lipid peroxidation in an iron- and ROS-dependent manner. Celastrol, a natural bioactive triterpenoid extracted from Tripterygium wilfordii, shows effective anti-fibrotic and anti-inflammatory activities in multiple he...
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| Main Authors: | , , , , , , , , , , , , |
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| Format: | Book |
| Published: |
Elsevier,
2022-05-01T00:00:00Z.
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| Subjects: | |
| Online Access: | Connect to this object online. |
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