Biological activity of synthesized 5-{1-[(4-chlorophenyl)sulfonyl]piperidin-4-yl}-2-mercapto-1,3,4-oxadiazole derivatives demonstrated by in silico and BSA binding studies

• Hoofdauteurs: Javed Iqbal (Auteur), Aziz- (Auteur), Muhammad Athar Abbasi (Auteur), Sabahat Zahra Siddiqui (Auteur), Shahid Rasool (Auteur), Muhammad Ashraf (Auteur), Ambar Iqbal (Auteur), Sujhla Hamid (Auteur), Tahir Ali Chohan (Auteur), Hira Khalid (Auteur), Sabina Jhaumeer Laulloo (Auteur), Syed Adnan Ali Shah (Auteur)
• Formaat: Boek
• Gepubliceerd in: Universidade de São Paulo, 2020-12-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

We synthesized a series of compounds bearing pharmacologically important 1,3,4-oxadiazole and piperidine moieties. Spectral data analysis by 1H-NMR, 13C-NMR, IR and EI-MS was used to elucidate the structures of the synthesized molecules. Docking studies explained the different types of interaction o...