Nanocomplexes loaded with miR-128-3p for enhancing chemotherapy effect of colorectal cancer through dual-targeting silence the activity of PI3K/AKT and MEK/ERK pathway

• Main Authors: Xin Liu (Author), Chao Dong (Author), Siping Ma (Author), Yongpeng Wang (Author), Tao Lin (Author), Yanxi Li (Author), Shihua Yang (Author), Wanchuan Zhang (Author), Rui Zhang (Author), Guohua Zhao (Author)
• Format: Book
• Published: Taylor & Francis Group, 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Although microRNAs (miRNAs)-based cancer therapy strategies have been proved to be efficient and superior to chemotherapeutic agents in certain extent, the unstable properties of miRNAs significantly impaired the wide application. Therefore, how to safely deliver the miRNAs to the targeted site of a...