A validated UPLCâMS/MS method for simultaneous determination of imatinib, dasatinib and nilotinib in human plasma

• Main Authors: Jing Zeng (Author), Hua lin Cai (Author), Zhi ping Jiang (Author), Qing Wang (Author), Yan Zhu (Author), Ping Xu (Author), Xie lan Zhao (Author)
• Format: Book
• Published: Elsevier, 2017-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

A sensitive, rapid, simple and economical ultra-performance liquid chromatographyâtandem mass spectrometric method (UPLCâMS/MS) was developed and validated for simultaneous determination of imatinib, dasatinib and nilotinib in human plasma using gliquidone as internal standard (IS). Liquid-liquid ex...