A statistical framework for analyzing hypothesized interactions between cells imaged using multispectral microscopy and multiple immunohistochemical markers

• Glavni autori: Chris J Rose (Autor), Khimara Naidoo (Autor), Vanessa Clay (Autor), Kim Linton (Autor), John A Radford (Autor), Richard J Byers (Autor)
• Format: Knjiga
• Izdano: Elsevier, 2013-01-01T00:00:00Z.
• Teme: article
• Online pristup: Connect to this object online.

Background: Multispectral microscopy and multiple staining can be used to identify cells with distinct immunohistochemical (IHC) characteristics. We present here a method called hypothesized interaction distribution (HID) analysis for characterizing the statistical distribution of pair-wise spatial...