Zebrafish neurofibromatosis type 1 genes have redundant functions in tumorigenesis and embryonic development

• المؤلفون الرئيسيون: Jimann Shin (مؤلف), Arun Padmanabhan (مؤلف), Eric D. de Groh (مؤلف), Jeong-Soo Lee (مؤلف), Sam Haidar (مؤلف), Suzanne Dahlberg (مؤلف), Feng Guo (مؤلف), Shuning He (مؤلف), Marc A. Wolman (مؤلف), Michael Granato (مؤلف), Nathan D. Lawson (مؤلف), Scot A. Wolfe (مؤلف), Seok-Hyung Kim (مؤلف), Lilianna Solnica-Krezel (مؤلف), John P. Kanki (مؤلف), Keith L. Ligon (مؤلف), Jonathan A. Epstein (مؤلف), A. Thomas Look (مؤلف)
• التنسيق: كتاب
• منشور في: The Company of Biologists, 2012-11-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

SUMMARY Neurofibromatosis type 1 (NF1) is a common, dominantly inherited genetic disorder that results from mutations in the neurofibromin 1 (NF1) gene. Affected individuals demonstrate abnormalities in neural-crest-derived tissues that include hyperpigmented skin lesions and benign peripheral nerve...