Synthesis and Biological Evaluation of New Pyridothienopyrimidine Derivatives as Antibacterial Agents and <i>Escherichia coli</i> Topoisomerase II Inhibitors

• Main Authors: Eman M. Mohi El-Deen (Author), Eman A. Abd El-Meguid (Author), Eman A. Karam (Author), Eman S. Nossier (Author), Marwa F. Ahmed (Author)
• Format: Book
• Published: MDPI AG, 2020-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The growing resistance of bacteria to many antibiotics that have been in use for several decades has generated the need to discover new antibacterial agents with structural features qualifying them to overcome the resistance mechanisms. Thus, novel pyridothienopyrimidine derivatives (<b>2a<...