siRNA-Loaded Hydroxyapatite Nanoparticles for <i>KRAS</i> Gene Silencing in Anti-Pancreatic Cancer Therapy

• Main Authors: Dandan Luo (Author), Xiaochun Xu (Author), M. Zubair Iqbal (Author), Qingwei Zhao (Author), Ruibo Zhao (Author), Jabeen Farheen (Author), Quan Zhang (Author), Peiliang Zhang (Author), Xiangdong Kong (Author)
• Format: Book
• Published: MDPI AG, 2021-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Pancreatic carcinoma (PC) is greatly induced by the <i>KRAS</i> gene mutation, but effective targeted delivery for gene therapy has not existed. Small interfering ribonucleic acid (siRNA) serves as an advanced therapeutic modality and holds great promise for cancer treatment. However, th...