Bioactive Apigenin loaded oral nano bilosomes: Formulation optimization to preclinical assessment

• Main Authors: Ameeduzzafar Zafar (Author), Nabil K. Alruwaili (Author), Syed Sarim Imam (Author), Nasser Hadal Alotaibi (Author), Khalid Saad Alharbi (Author), Muhammad Afzal (Author), Raisuddin Ali (Author), Sultan Alshehri (Author), Sami I. Alzarea (Author), Mohammed Elmowafy (Author), Nabil A. Alhakamy (Author), Mohamed F. Ibrahim (Author)
• Format: Book
• Published: Elsevier, 2021-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Aim: Diabetic (type-2) is a metabolic disease characterized by increased blood glucose level from the normal level. In the present study, apigenin (AG) loaded lipid vesicles (bilosomes: BIL) was prepared, optimized and evaluated for the oral therapeutic efficacy. Experimental: AG-BIL was prepared by...