Involvement of Intracellular Ca2+ in the Regulatory Volume Decrease After Hyposmotic Swelling in MDCK Cells

• Váldodahkkit: Naoko Iida-Tanaka (Dahkki), Iyuki Namekata (Dahkki), Megumi Kaneko (Dahkki), Miku Tamura (Dahkki), Toru Kawanishi (Dahkki), Ryu Nakamura (Dahkki), Koki Shigenobu (Dahkki), Hikaru Tanaka (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: Elsevier, 2007-01-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

We examined the source of Ca2+ involved in the volume regulation of Madin-Darby canine kidney (MDCK) cells with confocal microscopy and fluoroprobes. Hyposmosis induced a transient increase in cell volume, as well as cytoplasmic Ca2+, which peaked at 3 to 5 min and gradually decreased to reach the i...