Traditional Chinese medicine Pien-Tze-Huang ameliorates LPS-induced sepsis through bile acid-mediated activation of TGR5-STAT3-A20 signalling

• Main Authors: Bei Li (Author), Yong Zhang (Author), Xinyuan Liu (Author), Ziyang Zhang (Author), Shuqing Zhuang (Author), Xiaoli Zhong (Author), Wenbo Chen (Author), Yilin Hong (Author), Pingli Mo (Author), Shuhai Lin (Author), Shicong Wang (Author), Chundong Yu (Author)
• Format: Book
• Published: Elsevier, 2024-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Pien Tze Huang (PZH), a class-1 nationally protected traditional Chinese medicine (TCM), has been used to treat liver diseases such as hepatitis; however, the effect of PZH on the progression of sepsis is unknown. Here, we reported that PZH attenuated lipopolysaccharide (LPS)-induced sepsis in mice...