Oncogenic ACSM6 impairs CD8+ T cell-based immune response in bladder cancer

• Main Authors: Zhenyu Nie (Author), Bolong Liu (Author), Jinhui Liu (Author), Xiongbing Zu (Author), Juanhua Wang (Author), Jinbo Chen (Author), Benyi Fan (Author), Dingshan Deng (Author)
• Format: Book
• Published: BMC, 2024-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Resistance to immunotherapy in bladder cancer has greatly limited its clinical application. Through single-cell sequencing, we determined that ACSM6, an oncogene that is highly expressed in bladder cancer, promotes the abilities of proliferation, cloning, migration, and invasion. The key po...