Itraconazole Promotes Macrophage M1 Polarization and Phagocytic Capacity of Macrophage to Candida Albicans

• Main Authors: Xiao-Li Zheng (Author), Guan-Zhao Liang (Author), Dong-Mei Shi (Author), Hui-Ping Yao (Author), Lu Zhang (Author), Wei-Da Liu (Author), Guan-Zhi Chen (Author)
• Format: Book
• Published: Wolters Kluwer Health, 2019-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract. Objective:. The present study was designed to evaluate whether and how itraconazole affects the macrophage polarization and its reactivity to Candida albicans. Methods:. Cell toxicity of itraconazole was measured using cell counting kit-8 assay in RAW264.7 cells. The cell models were induc...