Human Epididymis Secretory Protein 4 (HE4) Compromises Cytotoxic Mononuclear Cells via Inducing Dual Specificity Phosphatase 6

• Main Authors: Nicole E. James (Author), Matthew T. Oliver (Author), Jennifer R. Ribeiro (Author), Evelyn Cantillo (Author), Rachael B. Rowswell-Turner (Author), Kyu-Kwang Kim (Author), Clinton O. Chichester (Author), Paul A. DiSilvestro (Author), Richard G. Moore (Author), Rakesh K. Singh (Author), Naohiro Yano (Author), Ting C. Zhao (Author)
• Format: Book
• Published: Frontiers Media S.A., 2019-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

While selective overexpression of serum clinical biomarker Human epididymis secretory protein 4 (HE4) is indicative of ovarian cancer tumorigenesis, much is still known about the mechanistic role of the HE4 gene or gene product. Here, we examine the role of the secretory glycoprotein HE4 in ovarian...