Investigation of piperazines as human carbonic anhydrase I, II, IV and VII activators
Four human (h) carbonic anhydrase isoforms (CA, EC 4.2.1.1), hCA I, II, IV, and VII, were investigated for their activation profile with piperazines belonging to various classes, such as N-aryl-, N-alkyl-, N-acyl-piperazines as well as 2,4-disubstituted derivatives. As the activation mechanism invol...
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Main Authors: | Andrea Angeli (Author), Niccolò Chiaramonte (Author), Dina Manetti (Author), Maria Novella Romanelli (Author), Claudiu T. Supuran (Author) |
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Format: | Book |
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Taylor & Francis Group,
2018-01-01T00:00:00Z.
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