DNA Copy Number Aberrations and Expression of ABC Transporter Genes in Breast Tumour: Correlation with the Effect of Neoadjuvant Chemotherapy and Prognosis of the Disease

• Main Authors: Matvey M. Tsyganov (Author), Marina K. Ibragimova (Author), Kseniya A. Gaptulbarova (Author), Irina A. Tsydenova (Author), Daria S. Dolgasheva (Author), Evgeniy Y. Garbukov (Author), Anastasia A. Frolova (Author), Elena M. Slonimskaya (Author), Nikolai V. Litvyakov (Author)
• Format: Book
• Published: MDPI AG, 2022-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

One of the important reasons for the ineffectiveness of chemotherapy in breast cancer (BC) is considered to be the formation of a multidrug resistance phenotype in tumour cells, which is caused by the expression of energy-dependent ABC transporters. The aim of this work was to assess chromosomal abe...