In Vivo Delivery of miR-34a Sensitizes Lung Tumors to Radiation Through RAD51 Regulation

• Prif Awduron: Maria Angelica Cortez (Awdur), David Valdecanas (Awdur), Sharareh Niknam (Awdur), Heidi J Peltier (Awdur), Lixia Diao (Awdur), Uma Giri (Awdur), Ritsuko Komaki (Awdur), George A Calin (Awdur), Daniel R Gomez (Awdur), Joe Y Chang (Awdur), John Victor Heymach (Awdur), Andreas G Bader (Awdur), James William Welsh (Awdur)
• Fformat: Llyfr
• Cyhoeddwyd: Elsevier, 2015-01-01T00:00:00Z.
• Pynciau: article
• Mynediad Ar-lein: Connect to this object online.

MiR-34a, an important tumor-suppressing microRNA, is downregulated in several types of cancer; loss of its expression has been linked with unfavorable clinical outcomes in non-small-cell lung cancer (NSCLC), among others. MiR-34a represses several key oncogenic proteins, and a synthetic mimic of miR...