MicroRNA-34a (miR-34a) Mediates Retinal Endothelial Cell Premature Senescence through Mitochondrial Dysfunction and Loss of Antioxidant Activities

MicroRNA-34a (miR-34a) Mediates Retinal Endothelial Cell Premature Senescence through Mitochondrial Dysfunction and Loss of Antioxidant Activities

Stress-associated premature senescence (SAPS) is involved in retinal microvascular injury and diabetic retinopathy. We have investigated the role and mode of action of miR-34a in retinal endothelial cells senescence in response to glucidic stress. Human retinal microvascular endothelial cells (HuREC...

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Main Authors: Menaka C. Thounaojam (Author), Ravirajsinh N. Jadeja (Author), Marie Warren (Author), Folami L. Powell (Author), Raghavan Raju (Author), Diana Gutsaeva (Author), Sandeep Khurana (Author), Pamela M. Martin (Author), Manuela Bartoli (Author)
Format: Book
Published: MDPI AG, 2019-08-01T00:00:00Z.
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3rd Floor Main Library

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