Up-regulation of microRNA-93 inhibits TGF-β1-induced EMT and renal fibrogenesis by down-regulation of Orai1

• Principais autores: Jifang Ma (Autor), Lei Zhang (Autor), Jianbing Hao (Autor), Naqi Li (Autor), Jie Tang (Autor), Lirong Hao (Autor)
• Formato: Livro
• Publicado em: Elsevier, 2018-04-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

TGF-β1-induced excessive deposition of ECM and EMT process of tubular epithelial cells play critical roles in the development and progression of fibrosis in diabetic nephropathy (DN). Orai1 has been demonstrated to be involved in TGF-β1-induced EMT via TGF-β/Smad3 pathway. We are aimed to explore th...