Long Non-coding RNAs Rian and Miat Mediate Myofibroblast Formation in Kidney Fibrosis

• Main Authors: Roel Bijkerk (Author), Yu Wah Au (Author), Wendy Stam (Author), Jacques M. G. J. Duijs (Author), Angela Koudijs (Author), Ellen Lievers (Author), Ton J. Rabelink (Author), Anton Jan van Zonneveld (Author)
• Format: Book
• Published: Frontiers Media S.A., 2019-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

There is an increasing prevalence of chronic kidney disease (CKD), which associates with the development of interstitial fibrosis. Pericytes (perivascular fibroblasts) provide a major source of α-SMA-positive myofibroblasts that are responsible for the excessive deposition of extracellular matrix. I...