Obovatol Enhances Docetaxel-Induced Prostate and Colon Cancer Cell Death Through Inactivation of Nuclear Transcription Factor-κB

• Main Authors: So Yong Lee (Author), Jin Suk Cho (Author), Dong Yeon Yuk (Author), Dong Cheul Moon (Author), Jae Kyung Jung (Author), Hwan Soo Yoo (Author), Young Moon Lee (Author), Sang Bae Han (Author), Ki-Wan Oh (Author), Jin Tae Hong (Author)
• Format: Book
• Published: Elsevier, 2009-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Nuclear transcription factor-κB (NF-κB) is constitutively activated in prostate and colon cancers and is related with the resistance of cancer cells against chemotherapeutics. Previously, we found that obovatol, an active compound isolated from Magnolia obovata, inhibited cancer cell growth through...