Indole-3-Carbinol (I3C) Protects the Heart From Ischemia/Reperfusion Injury by Inhibiting Oxidative Stress, Inflammation, and Cellular Apoptosis in Mice

• Main Authors: Qi Li (Author), Boyu Xia (Author), Jingjing Wu (Author), Xiaomei Yuan (Author), Xu Lu (Author), Chao Huang (Author), Hongcheng Gu (Author), Koulong Zheng (Author), Qingsheng You (Author), Kun Liu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Strategies for treating myocardial ischemia in the clinic usually include re-canalization of the coronary arteries to restore blood supply to the myocardium. However, myocardial reperfusion insult often leads to oxidative stress and inflammation, which in turn leads to apoptosis and necrosis of myoc...