Differential Susceptibility of Bacteria to Mouse Paneth Cell a-Defensins under Anaerobic Conditions

• Main Authors: Jennifer R. Mastroianni (Author), Wuyuan Lu (Author), Michael E. Selsted (Author), André J. Ouellette (Author)
• Formato: Livro
• Publicado em: MDPI AG, 2014-10-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Small intestinal Paneth cells secrete a-defensin peptides, termed cryptdins (Crps) in mice, into the intestinal lumen, where they confer immunity to oral infections and define the composition of the ileal microbiota. In these studies, facultative bacteria maintained under aerobic or anaerobic condit...