Pharmacokinetic drug interactions of asciminib with the sensitive cytochrome P450 probe substrates midazolam, warfarin, and repaglinide in healthy participants

Abstract Asciminib, a first‐in‐class BCR‐ABL1 inhibitor that works by Specifically Targeting the ABL Myristoyl Pocket (STAMP), is a new treatment option for patients with chronic myeloid leukemia who no longer benefit from currently approved tyrosine kinase inhibitors. In vitro, asciminib reversibly...

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Main Authors: Matthias Hoch (Author), Tirtha Sengupta (Author), Florence Hourcade‐Potelleret (Author)
Format: Book
Published: Wiley, 2022-06-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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