Context matters - Daxx and Atrx are not robust tumor suppressors in the murine endocrine pancreas

Context matters - Daxx and Atrx are not robust tumor suppressors in the murine endocrine pancreas

Genome sequencing has revealed the importance of epigenetic regulators in tumorigenesis. The genes encoding the chromatin remodeling complex DAXX:ATRX are frequently mutated in pancreatic neuroendocrine tumors; however, the underlying mechanisms of how mutations contribute to tumorigenesis are only...

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Main Authors: Chang Sun (Author), Jeannelyn S. Estrella (Author), Elizabeth M. Whitley (Author), Gilda P. Chau (Author), Guillermina Lozano (Author), Amanda R. Wasylishen (Author)
Format: Book
Published: The Company of Biologists, 2022-08-01T00:00:00Z.
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