Mechanistic Modelling Identifies and Addresses the Risks of Empiric Concentration-Guided Sorafenib Dosing
The primary objective of this study is to evaluate the capacity of concentration-guided sorafenib dosing protocols to increase the proportion of patients that achieve a sorafenib maximal concentration (C<sub>max</sub>) within the range 4.78 to 5.78 μg/mL. A full physiologically based pha...
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Format: | Book |
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MDPI AG,
2021-04-01T00:00:00Z.
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A1234.567 |
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