Synthesis, in vivo and in silico analgesic and anti-inflammatory studies of α-D-ribofuranose derivatives

• Hauptverfasser: Sabiha Enam Spriha (Verfasst von), Fahad Imtiaz Rahman (Verfasst von), S. M. Abdur Rahman (Verfasst von)
• Format: Buch
• Veröffentlicht: Elsevier, 2021-09-01T00:00:00Z.
• Schlagworte: article
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Five α-D-ribofuranose analogues (2, 3, 4, 5 and 6) were synthesized in good yields from 3-O-benzyl-4-C-(hydroxymethyl)-1, 2-O-isopropylidene-α-D-ribofuranose (1). The synthesized compounds were then subjected to analgesic, anti-inflammatory, antimicrobial and antioxidant assays. Compound 3 demonstra...