Effervescent N-Acetylcysteine Tablets versus Oral Solution N-Acetylcysteine in Fasting Healthy Adults: An Open-Label, Randomized, Single-Dose, Crossover, Relative Bioavailability Study

• Príomhchruthaitheoirí: Spencer C. Greene, MD, FACEP, FACMT (Údar), Patrick K. Noonan, PhD (Údar), Carlos Sanabria, MD, FACP (Údar), W. Frank Peacock, MD, FACEP, FACC (Údar)
• Formáid: LEABHAR
• Foilsithe / Cruthaithe: Elsevier, 2016-01-01T00:00:00Z.
• Ábhair: article
• Rochtain ar líne: Connect to this object online.

Background: Oral solution N-acetylcysteine (NAC) is an antidote for acetaminophen overdose, but its unpleasant taste and aroma can impede delivery even after the coadministration of antiemetic medications. Flavored effervescent NAC tablets dissolved in water might be a more palatable formulation tha...