Novel 4-arylaminoquinazolines bearing N,N-diethyl(aminoethyl)amino moiety with antitumour activity as EGFRwt-TK inhibitor

Herein, four novel 4-arylaminoquinazoline derivatives with N,N-diethyl(aminoethyl)amino moiety were designed, synthesised and evaluated on biological activities in vitro. All synthesised compounds have inhibitory effects against tumour cells (SW480, A549, A431 and NCI-H1975). In particular, 4-(3-chl...

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Main Authors: Yaling Zhang (Author), Li Chen (Author), Xiabing Li (Author), Li Gao (Author), Yunxia Hao (Author), Baolin Li (Author), Yaping Yan (Author)
Format: Book
Published: Taylor & Francis Group, 2019-01-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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