KR-31466, a Benzopyranylindol Analog, Attenuates Hypoxic Injury Through Mitochondrial KATP Channel and Protein Kinase C Activation in Heart-Derived H9c2 Cells

• Main Authors: Yi-Sook Jung (Author), Yoon Seok Jung (Author), Mi-Young Kim (Author), Min Hwa Kim (Author), Sunkyung Lee (Author), Kyu Yang Yi (Author), Sung Eun Yoo (Author), Soo Hwan Lee (Author), Eun Joo Baik (Author), Chang-Hyun Moon (Author), Joon Pil Cho (Author)
• Format: Book
• Published: Elsevier, 2003-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In the present study, we investigated whether a novel benzopyranylindol analogue, KR-31466 (KR466) (1-[(2S,3R,4S)-3,4-dihydro-2-dimethoxymethyl-3-hydroxy-2-methyl-6-nitro-2H-1-benzopyran-4-yl]-1H-indole-2-carboxylic acid ethyl ester) can attenuate hypoxic injury in heart-derived H9c2 cells and, if s...