Different response of embryos originating from control and obese mice to insulin in vitro

• Main Authors: Martina KŠIŇANOVÁ (Author), Veronika KOVAŘÍKOVÁ (Author), Zuzana ŠEFČÍKOVÁ (Author), Alexandra ŠPIRKOVÁ (Author), Štefan ČIKOŠ (Author), Jozef PISKO (Author), Dušan FABIAN (Author)
• Format: Book
• Published: The Society for Reproduction and Development, 2020-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The aim of the present work was to investigate the impact of maternal obesity on DNA methylation in ovulated oocytes, and to compare the response of in vitro-developing preimplantation embryos originating from control and obese mice to insulin. An intergenerational, diet-induced obesity model was us...