The −675 4G/5G PAI-1 polymorphism confers genetic susceptibility to systemic lupus erythematosus, its clinical manifestations, and comorbidities in Mexican-Mestizo population

• Main Authors: B. U. Anaya-Macias (Author), U. De la Cruz-Mosso (Author), C. A. Palafox-Sánchez (Author), I. Parra-Rojas (Author), G. Martínez-Bonilla (Author), L. González-López (Author), J. I. Gámez-Nava (Author), E. E. Pérez-Guerrero (Author), S. L. Barrientos-Avalos (Author), J. F. Muñoz-Valle (Author)
• Format: Book
• Published: Taylor & Francis Group, 2020-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Systemic lupus erythematosus (SLE) involves a broad range of factors that contribute to the development of the disease and its comorbidities. Genetic predisposition influences the development of SLE, and the −675 4G/5G PAI-1 polymorphism has been associated with several pathologies with a chronic in...