Safety Evaluation of Nano-Liposomal Formulation of Amphotericin B (SinaAmpholeish) in Animal Model as a Candidate for Treatment of Cutaneous Leishmaniasis

• Main Authors: Seyed Ebrahim Eskandari (Author), Alireza Firooz (Author), Mansour Nassiri-Kashani (Author), Mahmoud Reza Jaafari (Author), Amir Javadi (Author), Akram Miramin-Mohammadi (Author), Hossein Valian-Keshavarz (Author), Ali Khamesipour (Author)
• Format: Book
• Published: Tehran University of Medical Sciences, 2018-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Development of a topical treatment for cutaneous leishmaniasis (CL) is an important step in the im­provement of lesion management. Amphotericin B (AmB) is effective against Leishmania species but it is toxic, a Nano-liposomal form of AmB with a size of about 100nm (Lip-AmB) was developed...